| RA is a chronic, progressive disease. In the most advanced stages, affected joints can become grossly deformed and dysfunctional, tendons can rupture, and bone can be destroyed. Most individuals experience remissions and flare-ups (exacerbations) of the disease over time. Up to 75% of individuals with RA improve symptomatically with treatment, but 10% become severely disabled, even with full treatment (Beers). Research studies have shown that life expectancy is reduced in patients with RA by 3 to 18 years. |
Source: Medical Disability Advisor