| Free air or gas within the pleural cavity (pneumothorax) or the abnormal presence of air in tissues that separate parts of the lung cavity (pneumomediastinum) can develop during severe asthma attacks, especially if the individual requires mechanical ventilation. A severe asthma attack that does not respond to treatment can lead to prolonged contraction (bronchospasm) of smooth muscles (status asthmaticus) and may be followed by respiratory failure and death. Individuals who have chronic pulmonary disease in addition to asthma will often have more severe and debilitating episodes of asthma.
Long-term oral steroid use by asthmatics can lead to blood chemistry disturbances, cataracts, osteoporosis, immunosuppression, and adrenal suppression. Over-treatment of asthma with bronchodilators may precipitate cardiac arrhythmia. |
Source: Medical Disability Advisor