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Sedentary Work Exerting up to 10 pounds (4.5 kg) of force occasionally and/or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects, including the human body. Sedentary work involves sitting most of the time, but may involve walking or standing for brief periods of time. Jobs are sedentary if walking and standing are required only occasionally and other sedentary criteria are met.

Light Work Exerting up to 20 pounds (9.1 kg) of force occasionally and/or up to 10 pounds (4.5 kg) of force frequently, and/or negligible amount of force constantly to move objects. Physical demand requirements are in excess of those for Sedentary Work. Light Work usually requires walking or standing to a significant degree. However, if the use of the arm and/or leg controls requires exertion of forces greater than that for Sedentary Work and the worker sits most the time, the job is rated Light Work.

Medium Work Exerting up to 50 (22.7 kg) pounds of force occasionally, and/or up to 25 pounds (11.3 kg) of force frequently, and/or up to 10 pounds (4.5 kg) of forces constantly to move objects.

Heavy Work Exerting up to 100 pounds (45.4 kg) of force occasionally, and/or up to 50 pounds (22.7 kg) of force frequently, and/or in excess of 20 pounds (9.1 kg) of force constantly to move objects.

Very Heavy Work Exerting in excess of 100 pounds (45.4 kg) of force occasionally, and/or in excess of 50 pounds (22.7 kg) of force frequently, and/or in excess of 20 pounds (9.1 kg) of force constantly to move objects.

Job Classification

In most duration tables, five job classifications are displayed. These job classifications are based on the amount of physical effort required to perform the work. The classifications correspond to the Strength Factor classifications described in the United States Department of Labor's Dictionary of Occupational Titles. The following definitions are quoted directly from that publication.

Sedentary Work Exerting up to 10 pounds (4.5 kg) of force occasionally and/or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects, including the human body. Sedentary work involves sitting most of the time, but may involve walking or standing for brief periods of time. Jobs are sedentary if walking and standing are required only occasionally and other sedentary criteria are met.

Light Work Exerting up to 20 pounds (9.1 kg) of force occasionally and/or up to 10 pounds (4.5 kg) of force frequently, and/or negligible amount of force constantly to move objects. Physical demand requirements are in excess of those for Sedentary Work. Light Work usually requires walking or standing to a significant degree. However, if the use of the arm and/or leg controls requires exertion of forces greater than that for Sedentary Work and the worker sits most the time, the job is rated Light Work.

Medium Work Exerting up to 50 (22.7 kg) pounds of force occasionally, and/or up to 25 pounds (11.3 kg) of force frequently, and/or up to 10 pounds (4.5 kg) of forces constantly to move objects.

Heavy Work Exerting up to 100 pounds (45.4 kg) of force occasionally, and/or up to 50 pounds (22.7 kg) of force frequently, and/or in excess of 20 pounds (9.1 kg) of force constantly to move objects.

Very Heavy Work Exerting in excess of 100 pounds (45.4 kg) of force occasionally, and/or in excess of 50 pounds (22.7 kg) of force frequently, and/or in excess of 20 pounds (9.1 kg) of force constantly to move objects.

Bone Marrow or Hematopoietic Stem Cell Transplant


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Complications

Several complications may arise prior to transplant due to the necessary intensive preparative treatment of chemotherapy and radiation therapy. The intensity of this pretreatment regimen varies based on the type of donor and the underlying condition of the recipient. These preparative regimens, particularly the very intense regimens, often result in a number of adverse effects that may be lethal. The most common life-threatening pretreatment complication is hepatic veno-occlusive disease, a disorder which literally chokes the circulation to the liver causing liver dysfunction and multiple organ failure in 20% of affected individuals. Another pretreatment complication is hemorrhagic cystitis (bleeding from the bladder) which occurs in 5% to 50% of those who had preparatory treatment with a high-dose chemotherapeutic drug called cyclophosphamide. The hemorrhagic cystitis usually resolves, but may cause urinary tract scarring and dysfunction.

Following transplant, there are two possible transplant-related complications. Graft-versus-host-disease (GVHD) occurs in approximately 50% of individuals who have undergone allogeneic bone marrow transplant. The donor immune-system cells attack the cells of the recipient, because they appear foreign (not genetically matched). This attack may cause severe immune system and organ system dysfunction in the transplant recipient. The second complication is graft rejection, in which the donor cells fail to regenerate as expected. This complication occurs in approximately 1% to 2% of sibling-matched allografts and significantly more frequently in unrelated donor transplants (Efiom-Ekaha). Other complications associated with a bone marrow transplant procedure include bleeding, post-transplant immunodeficiency, hypothyroidism, respiratory arrest, renal failure, pneumonia, allergic reactions, fever, anaphylactic shock, air embolism, and development of a second malignancy.

Source: Medical Disability Advisor