Wound infection results from microbes flourishing in the surgical site because of poor quality of tissue, limited vascular supply to wound area, poor preoperative preparation, wound contamination, poor antibiotic selection, or the inability of an immunocompromised patient to fight off infection. Contamination of the wound is present to some extent in all incisions; a setback in recovery such as malnutrition, cardiac failure, or decreased oxygen to the tissues will weaken the individual and allow the infection to take hold.
Abdominal surgeries, lengthy surgeries (lasting over 2 hours), contaminated operations, and the presence of multiple (more than 3) diagnoses in the individual present the highest risk. Generally, factors increasing an individual's risk include advanced age, obesity, malnutrition, decreased blood volume, lengthy preoperative stay, hypothermia, poor tissue perfusion, diabetes, and the use of immunosuppressants such as steroids. Certain wound characteristics may also factor into surgical site infection (SSI), including dead tissue, poor skin preparation, and wound drains. Additionally, conditions surrounding the surgery may account for added risk; among them are surgical technique, wound site contamination, infection among the surgical staff, and instrument contamination. Preoperative antibiotic prophylaxis, good isolation techniques and delayed suturing of contaminated or infected wounds will lower the risk of postoperative wound infection. |
Source: Medical Disability Advisor